OUR RESEARCH

Peer-reviewed research from our team on the biology of exercise.

  1. Orange ST, Dodd E, Nath S, Bowden H, Jordan AR, Tweddle H, Hedley A, Chukwuma I, Hickson I, Sharma Saha S.

    Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells.

    International Journal of Cancer 2026, 158(10), 2641-2649.

  2. Thomas C, Kudiersky N, Ansdell P, Ashton RE, Brown C, Bewick T, Carr J, Hume E, Spillane P, Pastorio E, Owen R, Maden-Wilkinson T, McNeil-Angopa E, Parkington T, Arena R, Ozemek C, Formenti F, Veluswamy SK, Gururaj R, Faghy MA.

    Submaximal 2-day cardiopulmonary exercise testing to assess exercise capacity and post-exertional symptom exacerbation in people with long COVID.

    Experimental Physiology 2026, 111(2), 435-448.

  3. Orange ST, Leslie J, Ross M, Mann DA, Wackerhage H.

    The exercise IL-6 enigma in cancer.

    Trends in Endocrinology and Metabolism 2023, 34(11), 749-763.

  4. Orange ST, Jordan AR, Odell A, Kavanagh O, Hicks KM, Eaglen T, Todryk S, Saxton JM.

    Acute aerobic exercise-conditioned serum reduces colon cancer cell proliferation in vitro through interleukin-6-induced regulation of DNA damage.

    International Journal of Cancer 2022, 151(2), 265-274.

  5. Kordi M, Simpson LP, Thomas K, Goodall S, Maden-Wilkinson T, Menzies C, Howatson G.

    The relationship between neuromuscular function and the W′ in elite cyclists.

    International Journal of Sports Physiology and Performance 2021, 16(11), 1656-1662.

  6. Metcalfe R, Kemp R, Heffernan SM, Churm R, Chen Y, Ruffino JS, Conway GE, Tornillo G, Orange ST.

    Anti-carcinogenic effects of exercise-conditioned human serum: evidence, relevance and opportunities.

    European Journal of Applied Physiology 2021, 121, 2107-2124.

  7. Orange ST, Jordan AR, Saxton JM.

    The serological responses to acute exercise in humans reduce cancer cell growth in vitro: A systematic review and meta-analysis.

    Physiological Reports 2020, 8(22), e14635.

  8. Kordi M, Folland J, Goodall S, Haralabidis N, Maden-Wilkinson T, Patel TS, Leeder J, Barratt P, Howatson G.

    Mechanical and morphological determinants of peak power output in elite cyclists.

    Scandinavian Journal of Medicine & Science in Sports 2020, 30(2), 227-237.

  9. Ndjavera W, Orange ST, O'Doherty AF, Leicht AS, Rochester M, Mills R, Saxton JM.

    Exercise-induced attenuation of treatment side-effects in patients with newly diagnosed prostate cancer beginning androgen-deprivation therapy: a randomised controlled trial.

    BJU International 2020, 125(1), 28-37.

  10. Coulson J, Bagley L, Barnouin Y, Bradburn S, Butler-Browne G, Gapeyeva H, Hogrel JY, Maden-Wilkinson T, Maier AB, Meskers C, Murgatroyd C, Narici M, Pääsuke M, Sassano L, Sipilä S, Al-Shanti N, Stenroth L, Jones DA, McPhee JS.

    Circulating levels of dickkopf-1, osteoprotegerin and sclerostin are higher in old compared with young men and women and positively associated with whole-body bone mineral density in older adults.

    Osteoporosis International 2017, 28(9), 2683-2689.